An original 3D numerical approach for fluid flow in fractured porous media is proposed. The whole research domain is discretized by the Delaunay tetrahedron based on the concept of node saturation. Tetrahedral blocks are impermeable, and fluid only flows through the interconnected interfaces between blocks. Fractures and the porous matrix are replaced by the triangular interface network, which is the so-called equivalent matrix-fracture network (EMFN). In this way, the three-dimensional seepage problem becomes a two-dimensional problem. The finite element method is used to solve the steady-state flow problem. The big finding is that the ratio of the macroconductivity of the whole interface network to the local conductivity of an interface is linearly related to the cubic root of the number of nodes used for mesh generation. A formula is presented to describe this relationship. With this formula, we can make sure that the EMFN produces the same macroscopic hydraulic conductivity as the intact rock. The approach is applied in a series of numerical tests to demonstrate its efficiency. Effects of the hydraulic aperture of fracture and connectivity of the fracture network on the effective hydraulic conductivity of fractured rock masses are systematically investigated.